apalutamide will reduce the level or effect of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP2C19 inducer, with drugs that are CYP2C19 substrates can lead to reduced exposure to these prescription drugs.I like that I have an instantaneous-use seizure mediā€¦ Read More